Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011378)
Formula
SVG example
Unclear
Reactant LEE011 Metabolite M15 Product LEE011 Metabolite M4
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011376 LEE011 LEE011 Metabolite M15 Unclear - Unclear LEE011 [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011377 LEE011 Metabolite M15 LEE011 Metabolite M1 Unclear - Unclear LEE011 [1]
References
1 An integrated assessment of the ADME properties of the CDK4/6 Inhibitor ribociclib utilizing preclinical in vitro, in vivo, and human ADME data

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