Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011431)
Formula Reactant Reduction of Desmethyl futibatinib Product Reduction of bisdesmethyl futibatinib
Reactant Info Product Info
Metabolic Type Oxidation - O-demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011428 Desmethyl futibatinib Reduction of Desmethyl futibatinib Unclear - Unclear TAS-120 [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011432 Reduction of Desmethyl futibatinib Reduction hydrolysed desmethyl futibatinib Other reaction - Hydration TAS-120 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011433 Reduction of bisdesmethyl futibatinib TAS-120 Metabolite F5 Oxidation - Oxidation TAS-120 [1]
References
1 Evaluation of the Mass Balance and Metabolic Profile of Futibatinib in Healthy Participants

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