Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011601)
Formula	ADH4 Unclear
	Reactant	Tivantinib Metabolite M8 precursor	Product	Tivantinib Metabolite M8
	Reactant	Reactant Info	Product	Product Info
Metabolic Enzyme	Alcohol dehydrogenase class-II (ADH4)				DME Info
Metabolic Type	Unclear - Unclear

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR011600	Tivantinib	Tivantinib Metabolite M8 precursor	Unclear - Unclear	Tivantinib	[1]

Other MR(s) Related to The Product of This MR

Other MR(s) That Metabolize The Produtc of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR011602	Tivantinib Metabolite M8	Tivantinib Metabolite M9	Oxidation - Oxidation	Tivantinib	[1]

References
1	Stereoselective hydroxylation by CYP2C19 and oxidation by ADH4 in the in vitro metabolism of tivantinib

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