Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011605)
Formula
SVG example
Unclear
Reactant Tivantinib Metabolite M4 Product Tivantinib Metabolite M15,16
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronosyltransferase 1A9 (UGT1A9) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011603 Tivantinib Tivantinib Metabolite M4 Unclear - Unclear Tivantinib [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011606 Tivantinib Metabolite M4 Tivantinib Metabolite M11 Oxidation - Oxidation Tivantinib [1]
MR011604 Tivantinib Metabolite M4 Tivantinib Metabolite M6 Unclear - Unclear Tivantinib [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011608 Tivantinib Metabolite M5 Tivantinib Metabolite M15,16 Unclear - Unclear Tivantinib [1]
References
1 Stereoselective hydroxylation by CYP2C19 and oxidation by ADH4 in the in vitro metabolism of tivantinib

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