Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011603)
Formula
CYP3A4 ...
SVG example
Unclear
Reactant Tivantinib Product Tivantinib Metabolite M4
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 3A5 (CYP3A5) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011610 Tivantinib Tivantinib Metabolite M10 Oxidation - Oxidation Tivantinib [1]
MR011607 Tivantinib Tivantinib Metabolite M5 Unclear - Unclear Tivantinib [1]
MR011600 Tivantinib Tivantinib Metabolite M8 precursor Unclear - Unclear Tivantinib [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011606 Tivantinib Metabolite M4 Tivantinib Metabolite M11 Oxidation - Oxidation Tivantinib [1]
MR011605 Tivantinib Metabolite M4 Tivantinib Metabolite M15,16 Unclear - Unclear Tivantinib [1]
MR011604 Tivantinib Metabolite M4 Tivantinib Metabolite M6 Unclear - Unclear Tivantinib [1]
References
1 Stereoselective hydroxylation by CYP2C19 and oxidation by ADH4 in the in vitro metabolism of tivantinib

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