Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012083)
Formula Reactant Brivanib Product Brivanib Metabolites M7
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1A2 (CYP1A2) DME Info
Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012088 Brivanib Brivanib Metabolites M25 Unclear - Unclear Brivanib [1]
MR012090 Brivanib Brivanib Metabolites M31 Unclear - Unclear Brivanib [1]
MR012097 Brivanib Brivanib Metabolites M25 Unclear - Unclear BMS-582664 [1]
MR012099 Brivanib Brivanib Metabolites M31 Unclear - Unclear BMS-582664 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012086 Brivanib Metabolites M7 Brivanib Metabolites M19 Unclear - Unclear Brivanib [1]
MR012084 Brivanib Metabolites M7 Brivanib Metabolites M26 Unclear - Unclear Brivanib [1]
MR012095 Brivanib Metabolites M7 Brivanib Metabolites M19 Unclear - Unclear BMS-582664 [1]
MR012093 Brivanib Metabolites M7 Brivanib Metabolites M26 Unclear - Unclear BMS-582664 [1]
References
1 Identification of the oxidative and conjugative enzymes involved in the biotransformation of brivanib

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