Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012382)
Formula
CYP3A4 ...
SVG example
N-deethylation
Reactant AZD-2327 Product N-deethylated AZD-2327
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 3A5 (CYP3A5) DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Oxidation - N-deethylation
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012293 2'3'-Dideoxyinosine DdA-TP Unclear - Unclear 2'3'-Dideoxyinosine [1]
References
1 Simultaneous determination of 2',3'-dideoxyinosine and the active metabolite, 2',3'-dideoxyadenosine-5'-triphosphate in human peripheral-blood mononuclear cell by HPLC-MS/MS and the application to cell pharmacokinetics

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