Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012738)
Formula Reactant Y-amino-butyraldehyde Product GABA
Reactant Info Product Info
Metabolic Enzyme Aldehyde dehydrogenase, dimeric NADP-preferring (ALDH3A1) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012737 Putrescine Y-amino-butyraldehyde Unclear - Unclear Arginine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012760 Gamma hydroxybutyric acid GABA Unclear - Unclear Gamma hydroxybutyric acid [2]
MR012753 L-glutamic acid GABA Unclear - Unclear L-glutamic acid [3]
MR007655 Putrescine -aminobutyric acid Unclear Putrescine [4]
MR001523 L-glutamate GABA Oxidation - Decarboxylation L-glutamine [5], [6]
MR003074 Gamma-guanidinobutyrate Gamma-aminobutyrate Unclear Agmatine [7]
MR012743 L-Glutamate GABA Unclear - Unclear Arginine [1]
⏷ Show the Full List of MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012761 GABA Glutamate Unclear - Unclear Gamma hydroxybutyric acid [2]
References
1 Arginine Metabolism Revisited
2 U. S. FDA Label -Gamma hydroxybutyric acid
3 Determination and Application of Nineteen Monoamines in the Gut Microbiota Targeting Phenylalanine, Tryptophan, and Glutamic Acid Metabolic Pathways
4 Human aldehyde dehydrogenase: metabolism of putrescine and histamine
5 Glutamate decarboxylase-dependent acid resistance in orally acquired bacteria: function, distribution and biomedical implications of the gadBC operon. Mol Microbiol. 2012 Nov;86(4):770-86.
6 The delta subunit of the GABA(A) receptor is necessary for the GPT2-promoted breast cancer metastasis. Theranostics. 2023 Feb 21;13(4):1355-1369. doi: 10.7150/thno.80544.
7 Metabolism and function in animal tissues of agmatine, a biogenic amine formed from arginine Amino Acids. 2004 Feb;26(1):3-8. doi: 10.1007/s00726-003-0030-z.

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