Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012740)
Formula
SVG example
Unclear
Reactant L-Ornithine Product Putrescine
Reactant Info Product Info
Metabolic Enzyme Ornithine decarboxylase (ODC1) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012739 Arginine L-Ornithine Unclear - Unclear Arginine [1]
MR007607 Delta-1-pyrroline-5-carboxylic acid Ornithine Unclear Proline [2]
MR008814 P5C Ornithine Unclear - Unclear L-Proline [3]
MR001525 1-pyrroline-5-carboxylic acid L-Ornithine Unclear L-glutamine [4]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012741 L-Ornithine L-Glutamyl-y-semialdehyde Unclear - Unclear Arginine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003066 Agmatine Putrescine Unclear Agmatine [5], [6], [7]
MR012734 L-Agmatine Putrescine Unclear - Unclear Arginine [1]
MR000577 N-Acetylspermidine Putrescine Unclear CCG-205124 [8]
References
1 Arginine Metabolism Revisited
2 Proline metabolism in cancer
3 Proline Metabolism in Cell Regulation and Cancer Biology: Recent Advances and Hypotheses
4 The Emerging Role of l-Glutamine in Cardiovascular Health and Disease Nutrients. 2019 Sep 4;11(9):2092. doi: 10.3390/nu11092092.
5 Metabolism and function in animal tissues of agmatine, a biogenic amine formed from arginine Amino Acids. 2004 Feb;26(1):3-8. doi: 10.1007/s00726-003-0030-z.
6 Genome-wide analysis of polyamine biosynthesis genes in wheat reveals gene expression specificity and involvement of STRE and MYB-elements in regulating polyamines under drought. BMC Genomics. 2022 Oct 30;23(1):734. doi: 10.1186/s12864-022-08946-2.
7 Unique Chemistry, Intake, and Metabolism of Polyamines in the Central Nervous System (CNS) and Its Body. Biomolecules. 2022 Mar 25;12(4):501. doi: 10.3390/biom12040501.
8 The Association between Spermidine/Spermine N(1)-Acetyltransferase (SSAT) and Human Malignancies Int J Mol Sci. 2022 May 25;23(11):5926. doi: 10.3390/ijms23115926.

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