General Information of This Metabolic Reaction (MR) (ID: MR000577)
Formula
SVG example
Reactant N-Acetylspermidine Product Putrescine
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000579 CCG-205124 N-Acetylspermidine Unclear CCG-205124 [1]
MR003935 SPD AcSPD N1-acetylspermidine Unclear KM-1406 [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003066 Agmatine Putrescine Unclear Agmatine [3], [4], [5]
MR012734 L-Agmatine Putrescine Unclear - Unclear Arginine [6]
MR012740 L-Ornithine Putrescine Unclear - Unclear Arginine [6]
MR008815 Ornithine Putrescine Unclear - Unclear L-Proline [7]
References
1 The Association between Spermidine/Spermine N(1)-Acetyltransferase (SSAT) and Human Malignancies Int J Mol Sci. 2022 May 25;23(11):5926. doi: 10.3390/ijms23115926.
2 Spermine metabolism and anticancer therapy
3 Metabolism and function in animal tissues of agmatine, a biogenic amine formed from arginine Amino Acids. 2004 Feb;26(1):3-8. doi: 10.1007/s00726-003-0030-z.
4 Genome-wide analysis of polyamine biosynthesis genes in wheat reveals gene expression specificity and involvement of STRE and MYB-elements in regulating polyamines under drought. BMC Genomics. 2022 Oct 30;23(1):734. doi: 10.1186/s12864-022-08946-2.
5 Unique Chemistry, Intake, and Metabolism of Polyamines in the Central Nervous System (CNS) and Its Body. Biomolecules. 2022 Mar 25;12(4):501. doi: 10.3390/biom12040501.
6 Arginine Metabolism Revisited
7 Proline Metabolism in Cell Regulation and Cancer Biology: Recent Advances and Hypotheses

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