Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012858)
Formula
SVG example
Reactant Aniline Product 2-aminophenol
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012856 Aniline 4-aminophenol Oxidation - Aromatic hydroxylation Aniline [1]
MR012853 Aniline Acetanilide-d5 Unclear Aniline [2]
MR012857 Aniline N-Hydroxyaniline Oxidation - N-oxidation Aniline [3]
MR005146 Aniline 4-aminophenol Oxidation - Hydrolyzationn Phenazopyridine [4], [5], [6]
References
1 Aniline and its metabolites generate free radicals in yeast
2 Human metabolism and excretion kinetics of aniline after a single oral dose
3 Aniline derivative-induced methemoglobin in rats
4 Metabolism and disposition of phenazopyridine in rat
5 The metabolism and excretion of phenazopyridine hydrochloride in animals and man
6 Excretion of phenazopyridine and its metabolites in the urine of humans, rats, mice, and guinea pigs

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