Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012906)
Formula
SVG example
Reactant 4-Hydroxycyclophosphamide Product 4-Ketocyclophosphamide
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012897 Cyclobenzaprine 4-Hydroxycyclophosphamide Oxidation - 4-hydroxylation Cyclobenzaprine [1], [2]
MR009942 Cyclophosphamide 4-Hydroxycyclophosphamide Unclear - Unclear Cyclophosphamide [3]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009943 4-Hydroxycyclophosphamide Aldophosphamide Unclear - Unclear Cyclophosphamide [2]
MR012898 4-Hydroxycyclophosphamide Aldophosphamide Unclear Cyclobenzaprine [2]
References
1 The KEGG resource for deciphering the genome
2 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
3 Aprepitant inhibits cyclophosphamide bioactivation and thiotepa metabolism

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.