Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013045)
Formula
SVG example
Unclear
Reactant Darexaban glucuronide Product Darexaban maleate Metabolite M4
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013043 Darexaban maleate Darexaban glucuronide Unclear - Unclear Darexaban maleate [1], [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013044 Darexaban glucuronide Darexaban maleate Metabolite M2 Unclear - Unclear Darexaban maleate [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013040 Darexaban maleate Metabolite M5 Darexaban maleate Metabolite M4 Unclear - Unclear Darexaban maleate [1]
References
1 Absorption, metabolism and excretion of darexaban (YM150), a new direct factor Xa inhibitor in humans
2 Identification of UDP-glucuronosyltransferases responsible for the glucuronidation of darexaban, an oral factor Xa inhibitor, in human liver and intestine

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