Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013047)
Formula
SVG example
N-oxygenation
Reactant Ranitidine Product Ranitidine N-Oxide
Reactant Info Product Info
Metabolic Enzyme Dimethylaniline oxidase 3 (FMO3) DME Info
Metabolic Type Oxidation - N-oxygenation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013046 Ranitidine Desmethylranitidine Oxidation - N-demethylation Ranitidine [1]
MR013048 Ranitidine Ranitidine S-Oxide Oxidation - S-oxygenation Ranitidine [1]
References
1 Oxidation of ranitidine by isozymes of flavin-containing monooxygenase and cytochrome P450. Jpn J Pharmacol. 2000 Oct;84(2):213-20.

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