Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013538)
Formula
	Reactant	Sotorasib Metabolite M30	Product	Sotorasib Metabolite M61
	Reactant	Reactant Info	Product	Product Info

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR013532	Sotorasib Metabolite M12	Sotorasib Metabolite M30	Hydrolysis - Hydrolysis	Sotorasib	[1], [2]

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR013533	Sotorasib Metabolite M30	Sotorasib Metabolite M10	Hydrolysis - Hydrolysis	Sotorasib	[1]

References
1	Absorption, Distribution, Metabolism, and Excretion of [(14)C]-Sotorasib in Rats and Dogs: Interspecies Differences in Absorption, Protein Conjugation and Metabolism
2	Absorption, metabolism and excretion of [(14)C]-sotorasib in healthy male subjects: characterization of metabolites and a minor albumin-sotorasib conjugate

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