Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013697)
Formula Reactant BIA 9-1079 Product Opicapone metabolite M41
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013696 Opicapone BIA 9-1079 Reduction - Reduction Opicapone [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013701 BIA 9-1079 BIA 9-1101 Oxidation - 3\O\methylation Opicapone [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013700 Opicapone metabolite M41 BIA 9-3721 Unclear Opicapone [2]
MR013698 Opicapone metabolite M41 Opicapone metabolite M4 Unclear Opicapone [2]
References
1 Pharmacokinetics, pharmacodynamics and tolerability of opicapone, a novel catechol-O-methyltransferase inhibitor, in healthy subjects: prediction of slow enzyme-inhibitor complex dissociation of a short-living and very long-acting inhibitor
2 Metabolism and disposition of opicapone in the rat and metabolic enzymes phenotyping

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