Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013701)
Formula Reactant BIA 9-1079 Product BIA 9-1101
Reactant Info Product Info
Metabolic Type Oxidation - 3\O\methylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013696 Opicapone BIA 9-1079 Reduction - Reduction Opicapone [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013697 BIA 9-1079 Opicapone metabolite M41 Unclear Opicapone [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013707 Opicapone BIA 9-1101 Multi-steps Reaction - Methylation; reduction Opicapone [1]
MR013703 BIA 9-1106 BIA 9-1101 Unclear Opicapone [2]
References
1 Pharmacokinetics, pharmacodynamics and tolerability of opicapone, a novel catechol-O-methyltransferase inhibitor, in healthy subjects: prediction of slow enzyme-inhibitor complex dissociation of a short-living and very long-acting inhibitor
2 Metabolism and disposition of opicapone in the rat and metabolic enzymes phenotyping

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.