Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013775)
Formula Reactant Jatrorrhizine Product 3,10-demethylpalmatine
Reactant Info Product Info
Metabolic Type Oxidation - Demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013774 Berberine Jatrorrhizine Reduction - Reduction Berberine [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013784 Jatrorrhizine Jatrorrhizine-3-O-beta-D-glucuronide Conjugation - Glucuronidation Berberine [1]
MR013785 Jatrorrhizine Jatrorrhizine-3-O-sulfate Conjugation - Sulfation Berberine [1]
MR013786 Jatrorrhizine Palmatine Oxidation - Methylation Berberine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013776 3,10-demethylpalmatine 2,3,10-trihydroxyberberine Oxidation - Demethylation Berberine [1]
MR013778 3,10-demethylpalmatine 3,10-demethylpalmatine-10-O-sulfate Unclear - Unclear Berberine [1]
References
1 The metabolism of berberine and its contribution to the pharmacological effects

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