Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013811)
Formula
SVG example
Unclear
Reactant Methimazole M7 Product Methimazole M5b
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013810 Methimazole M6 Methimazole M7 Unclear - Unclear Methimazole [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013814 Methimazole M7 Methimazole M8 Unclear - Unclear Methimazole [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013817 Methimazole N-methylthiourea Unclear - Unclear Methimazole [1], [2]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013812 Methimazole M5b Methimazole M9 Unclear - Unclear Methimazole [1]
References
1 Evidence for the involvement of N-methylthiourea, a ring cleavage metabolite, in the hepatotoxicity of methimazole in glutathione-depleted mice: structure-toxicity and metabolic studies
2 Role of CYP2A6 in Methimazole Bioactivation and Hepatotoxicity

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