Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013812)
Formula	Unclear
	Reactant	Methimazole M5b	Product	Methimazole M9
	Reactant	Reactant Info	Product	Product Info
Metabolic Type	Unclear - Unclear

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR013817	Methimazole	N-methylthiourea	Unclear - Unclear	Methimazole	[1], [2]
MR013811	Methimazole M7	Methimazole M5b	Unclear - Unclear	Methimazole	[1]

Other MR(s) Related to The Product of This MR

Other MR(s) That Metabolize The Produtc of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR013813	Methimazole M9	Methimazole M10	Unclear - Unclear	Methimazole	[1]

References
1	Evidence for the involvement of N-methylthiourea, a ring cleavage metabolite, in the hepatotoxicity of methimazole in glutathione-depleted mice: structure-toxicity and metabolic studies
2	Role of CYP2A6 in Methimazole Bioactivation and Hepatotoxicity

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