Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00441)
Xenobiotics Name
Silybin
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
31553
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Cytochrome P450 2C9 (CYP2C9) DME Info Homo sapiens [1]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Cytochrome P450 2C9 (CYP2C9) DME Info IC50 = 18 microM [1]
References
1 Modulatory effects of silibinin in various cell signaling pathways against liver disorders and cancer - A comprehensive review. Eur J Med Chem. 2016 Nov 10;123:577-595.
2 Hydnocarpin-type flavonolignans: semisynthesis and inhibitory effects on Staphylococcus aureus biofilm formation. J Nat Prod. 2015 Aug 28;78(8):2095-103.

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