General Information of Xenobiotics (ID: XEO00758)
Xenobiotics Name
Grape seed proanthocyanidins
Xenobiotics Type
Natural Product(s), Extract(s) or Medicine(s)
Classification
Plant Extract
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Catalase (CAT) DME Info Homo sapiens [1]
Cytochrome P450 1A1 (CYP1A1) DME Info Homo sapiens [2]
Cytochrome P450 1B1 (CYP1B1) DME Info Homo sapiens [2]
Cytochrome P450 2E1 (CYP2E1) DME Info Homo sapiens [3]
Metallothionein-1A (MT1A) DME Info Homo sapiens [1]
Metallothionein-2A (MT2A) DME Info Homo sapiens [1]
Superoxide dismutase 1 (SOD1) DME Info Homo sapiens [1]
References
1 Dietary catechins and procyanidins modulate zinc homeostasis in human HepG2 cells. J Nutr Biochem. 2011 Feb;22(2):153-63.
2 Grape seed proanthocyanidin suppression of breast cell carcinogenesis induced by chronic exposure to combined 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and benzo[a]pyrene. Mol Carcinog. 2010 May;49(5):450-63.
3 Mechanistic pathways of antioxidant cytoprotection by a novel IH636 grape seed proanthocyanidin extract. Indian J Exp Biol. 2002 Jun;40(6):717-26.

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