General Information of Xenobiotics (ID: XEO00865)
Xenobiotics Name
Sanguinarine
Xenobiotics Type
Natural Product(s), Extract(s) or Medicine(s)
Classification
Natural Product
Structure
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3D MOL 2D MOL
PubChem CID
5154
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Cytochrome P450 1A1 (CYP1A1) DME Info Homo sapiens [1]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [2]
Quinone reductase 1 (NQO1) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Cytochrome P450 1B1 (CYP1B1) DME Info Homo sapiens [3]
References
1 Transcriptomic analysis of untreated and drug-treated differentiated HepaRG cells over a 2-week period. Toxicol In Vitro. 2015 Dec 25;30(1 Pt A):27-35.
2 Bacterial biofilm formation inhibitory activity revealed for plant derived natural compounds. Bioorg Med Chem. 2012 Jan 15;20(2):920-6.
3 PPARgama activation rescues mitochondrial function from inhibition of complex I and loss of PINK1. Exp Neurol. 2014 Mar;253:16-27.

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