Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00895)
Xenobiotics Name
2-amino-3-methylimidazo(4,5-f)quinoline
Xenobiotics Type
Health or Environmental Toxicant(s)
Classification
Carcinogen
Structure
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3D MOL 2D MOL
PubChem CID
53462
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Small intestine reductase (AKR1B10) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Cytochrome P450 1A1 (CYP1A1) DME Info Homo sapiens [2]
Cytochrome P450 1A2 (CYP1A2) DME Info Homo sapiens [2]
References
1 Oxidative stress mechanisms do not discriminate between genotoxic and nongenotoxic liver carcinogens. Chem Res Toxicol. 2015 Aug 17;28(8):1636-46.
2 Aryl hydrocarbon receptor activation and CYP1A induction by cooked food-derived carcinogenic heterocyclic amines in human HepG2 cell lines. Food Chem Toxicol. 2016 Nov;97:256-264.

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