Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00925)
Xenobiotics Name
BDE-99
Xenobiotics Type
Natural Product(s), Extract(s) or Medicine(s)
Classification
Natural Product
Structure
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3D MOL 2D MOL
PubChem CID
36159
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
N-acetyltransferase 1 (NAT1) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Asparagine synthetase (ASNS) DME Info Homo sapiens [2]
Serine sulfhydrase (CBS) DME Info Homo sapiens [3]
Cytochrome P450 1A1 (CYP1A1) DME Info Homo sapiens [4]
Cytochrome P450 1A2 (CYP1A2) DME Info Homo sapiens [5]
Cytochrome P450 1B1 (CYP1B1) DME Info Homo sapiens [6]
Cytochrome P450 3A4 (CYP3A4) DME Info Homo sapiens [5]
Glutathione S-transferase mu-1 (GSTM1) DME Info Homo sapiens [5]
Prostaglandin G/H synthase 2 (COX-2) DME Info Homo sapiens [7]
References
1 Global gene expression profiling of human bronchial epithelial cells exposed to airborne fine particulate matter collected from Wuhan, China. Toxicol Lett. 2014 Jul 3;228(1):25-33.
2 Effect of particulate matter 2.5 on gene expression profile and cell signaling in JEG-3 human placenta cells. Environ Toxicol. 2018 Nov;33(11):1123-1134.
3 Up-regulation of tissue factor in human pulmonary artery endothelial cells after ultrafine particle exposure. Environ Health Perspect. 2007 Apr;115(4):535-40.
4 Alteration of peripheral blood monocyte gene expression in humans following diesel exhaust inhalation. Inhal Toxicol. 2012 Feb;24(3):172-81.
5 Metabolism of polybrominated diphenyl ethers (PBDEs) by human hepatocytes in vitro. Environ Health Perspect. 2009 Feb;117(2):197-202.
6 Diesel exhaust particulate associated chemicals attenuate expression of CXCL10 in human primary bronchial epithelial cells. Toxicol In Vitro. 2017 Dec;45(Pt 3):409-416.
7 Transcriptome analysis of airborne PM2.5-induced detrimental effects on human keratinocytes. Toxicol Lett. 2017 May 5;273:26-35.

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