General Information of Xenobiotics (ID: XEO00951)
Xenobiotics Name
Hexachlorobenzene
Xenobiotics Type
Fungicide(s), Herbicide(s) or Insecticide(s)
Classification
Fungicide
Structure
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3D MOL 2D MOL
PubChem CID
8370
DME(s) Modulated by This Xenobiotics
DME(s) Induced by This Xenobiotics
Catechol O-methyltransferase (COMT) DME Info Homo sapiens [1]
Cholesterol desmolase (CYP11A1) DME Info Homo sapiens [1]
Cytochrome P450 1A1 (CYP1A1) DME Info Homo sapiens [1]
Prostaglandin G/H synthase 2 (COX-2) DME Info Homo sapiens [2]
References
1 Hexachlorobenzene and pentachlorobenzene accumulation, metabolism and effect on steroid secretion and on CYP11A1 and CYP19 expression in cultured human placental tissue. Reprod Toxicol. 2014 Jan;43:102-10.
2 Hexachlorobenzene promotes angiogenesis in vivo, in a breast cancer model and neovasculogenesis in vitro, in the human microvascular endothelial cell line HMEC-1. Toxicol Lett. 2015 Nov 19;239(1):53-64.

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