Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00998)
Xenobiotics Name
Butylbenzyl phthalate
Xenobiotics Type
Health or Environmental Toxicant(s)
Classification
Health Hazard/Toxicant
Structure
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3D MOL 2D MOL
PubChem CID
2347
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Catechol O-methyltransferase (COMT) DME Info Homo sapiens [1]
Aromatase (CYP19A1) DME Info Homo sapiens [2]
DME(s) Induced by This Xenobiotics
Cytochrome P450 1A1 (CYP1A1) DME Info Homo sapiens [3]
Cytochrome P450 1B1 (CYP1B1) DME Info Homo sapiens [3]
References
1 Assessment of cellular estrogenic activity based on estrogen receptor-mediated reduction of soluble-form catechol-O-methyltransferase (COMT) expression in an ELISA-based system. PLoS One. 2013 Sep 6;8(9):e74065.
2 Comparative toxicity, oxidative stress and endocrine disruption potential of plasticizers in JEG-3 human placental cells. Toxicol In Vitro. 2017 Feb;38:41-48.
3 Benzyl butyl phthalate induces necrosis by AhR mediation of CYP1B1 expression in human granulosa cells. Reprod Toxicol. 2012 Jan;33(1):67-75.

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