General Information of Xenobiotics (ID: XEO01293)
Xenobiotics Name
Ethyl isopropylamiloride
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Investigative Agent
Structure
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3D MOL 2D MOL
PubChem CID
1795
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Amiloride-sensitive amine oxidase (AOC1) DME Info Homo sapiens [1]
Cytochrome P450 1A1 (CYP1A1) DME Info Homo sapiens [2]
Cytochrome P450 1A2 (CYP1A2) DME Info Homo sapiens [2]
Cytochrome P450 1B1 (CYP1B1) DME Info Homo sapiens [2]
References
1 Diamine oxidase is the amiloride-binding protein and is inhibited by amiloride analogues. J Biol Chem. 1994 Apr 1;269(13):9921-5.
2 Inhibition of carcinogen-bioactivating cytochrome P450 1 isoforms by amiloride derivatives. Biochem Pharmacol. 2004 May 1;67(9):1711-9.

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