Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO01426)
Xenobiotics Name
Phencyclidine
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Drug Marketed but Withdrawn from Market
Structure
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3D MOL 2D MOL
PubChem CID
6468
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Cytochrome P450 2B6 (CYP2B6) DME Info Homo sapiens [1]
Mephenytoin 4-hydroxylase (CYP2C19) DME Info Homo sapiens [2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Cytochrome P450 2B6 (CYP2B6) DME Info Ki = 10 microM [1]
References
1 Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity. Curr Drug Metab. 2005 Oct;6(5):413-54.
2 Inhibition of human and rat 3beta-hydroxysteroid dehydrogenase and 17beta-hydroxysteroid dehydrogenase 3 activities by perfluoroalkylated substances. Chem Biol Interact. 2010 Oct 6;188(1):38-43.

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