Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO03693)
Xenobiotics Name	Kalata-B1
Xenobiotics Type	Amino Acid(s), Peptide(s) or Protein(s)
Classification	Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
	Beta-lactamase (blaB)	DME Info	Klebsiella oxytoca	[1]
	Unclear metabolic mechanism (DME-unclear)	DME Info	Klebsiella oxytoca	[1]
	Arylamine N-acetyltransferase (NAT)	DME Info	Klebsiella oxytoca	[1]
	NADPH-dependent oxidoreductase (nfrA)	DME Info	Staphylococcus aureus	[1]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data	Beta-lactamase (blaB)	DME Info	MIC = 54.8 microM	[1]
	Unclear metabolic mechanism (DME-unclear)	DME Info	MIC = 54.8 microM	[1]
	Arylamine N-acetyltransferase (NAT)	DME Info	MIC = 54.8 microM	[1]
	NADPH-dependent oxidoreductase (nfrA)	DME Info	MIC = 0.26 microM	[1]

References
1	Cyclotides insert into lipid bilayers to form membrane pores and destabilize the membrane through hydrophobic and phosphoethanolamine-specific interactions. J Biol Chem. 2012 Dec 21;287(52):43884-98.

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