General Information of Xenobiotics (ID: XEO05202)
Xenobiotics Name
Uperin-3.6
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Unclear metabolic mechanism (DME-unclear) DME Info Lactococcus lactis [1], [2]
Glutamate decarboxylase (gadB) DME Info Lactococcus lactis [1], [2]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [1], [2]
Tripeptidase (pepT) DME Info Lactococcus lactis [1], [2]
Dipeptidase (pepV) DME Info Lactococcus lactis [1], [2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Unclear metabolic mechanism (DME-unclear) DME Info MIC = 3 ug/ml [1], [2]
Glutamate decarboxylase (gadB) DME Info MIC = 3 ug/ml [1], [2]
NADPH-dependent oxidoreductase (nfrA) DME Info MIC = 25 ug/ml [1], [2]
Tripeptidase (pepT) DME Info MIC = 3 ug/ml [1], [2]
Dipeptidase (pepV) DME Info MIC = 3 ug/ml [1], [2]
References
1 Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance. Peptides. 2004 Jun;25(6):1035-54.
2 The solution structure of uperin 3.6, an antibiotic peptide from the granular dorsal glands of the Australian toadlet, Uperoleia mjobergii. J Pept Res. 1999 Aug;54(2):137-45.

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