Details of Drug-Metabolizing Enzyme (DME)
| General Information of DME (ID: DMEN081) | |||||
|---|---|---|---|---|---|
| DME Name | Nonenzymatical (Non-ME), . | ||||
| Gene Name | Non-ME | ||||
| Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME | |||||
| Full List of Drug(s) Metabolized by This DME | |||||
|---|---|---|---|---|---|
| Drugs in Phase 4 Clinical Trial | Click to Show/Hide the Full List of Drugs: 1 Drugs | ||||
D-Serine |
Drug Info | Phase 4 | Parkinsonism | ICD11: 8A00 | [1], [2] |
| References | |||||
|---|---|---|---|---|---|
| 1 | D-Serine made by serine racemase in Drosophila intestine plays a physiological role in sleep. Nat Commun. 2019 May 7;10(1):1986. | ||||
| 2 | D-Serine metabolism: new insights into the modulation of D-amino acid oxidase activity | ||||
| 3 | Uptake, Elimination, and Biotransformation Potential of a Progestagen (Cyproterone Acetate) in Tilapia Exposed at an Environmental Concentration | ||||
| 4 | Identification of the human P450 enzymes involved in lansoprazole metabolism. J Pharmacol Exp Ther. 1996 May;277(2):805-16. | ||||
| 5 | LABEL:LENVIMA- lenvatinib capsule | ||||
| 6 | Kinetics of intravenous melphalan Clin Pharmacol Ther. 1979 Jul;26(1):73-80. doi: 10.1002/cpt197926173. | ||||
| 7 | Clinical pharmacokinetics of tegaserod, a serotonin 5-HT(4) receptor partial agonist with promotile activity Clin Pharmacokinet. 2002;41(13):1021-42. doi: 10.2165/00003088-200241130-00002. | ||||
| 8 | Thalidomide metabolism and hydrolysis: mechanisms and implications | ||||
| 9 | Chiral inversion and hydrolysis of thalidomide: mechanisms and catalysis by bases and serum albumin, and chiral stability of teratogenic metabolites | ||||
If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.