| General Information of Drug Metabolite (DM) (ID: DM017379) |
| DM Name |
DXG-triphosphate (DXG-TP)
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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3-phosphoglycerate Kinase (3-PGK)
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DMEN772
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| Conjugation - Phosphorylation |
Amdoxovir
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[1] |
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creatine kinase (CKB)
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DMEN771
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| Conjugation - Phosphorylation |
Amdoxovir
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[1] |
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Nucleoside diphosphate kinase (NME4)
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DMEN006
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| Conjugation - Phosphorylation |
Amdoxovir
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[1] |
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pyruvate kinase M2 (PKM2)
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DMEN373
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| Conjugation - Phosphorylation |
Amdoxovir
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Amdoxovir |
DR4678
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Phase 2 |
Hepatitis B virus infection |
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| References |
| 1 |
Anabolism of amdoxovir: phosphorylation of dioxolane guanosine and its 5'-phosphates by mammalian phosphotransferases
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