Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000267)
Formula Reactant Apremilast metabolite M7 Product Apremilast metabolite M11
Reactant Info Product Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000279 Apremilast Apremilast metabolite M7 Oxidation - N-Deacetylation Apremilast [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000268 Apremilast metabolite M7 Apremilast metabolite M4 Oxidation - O-Demethylation Apremilast [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000269 Apremilast metabolite M11 Apremilast metabolite M8 Oxidation - Hydroxylation Apremilast [1]
References
1 Disposition, metabolism and mass balance of [(14)C]apremilast following oral administration. Xenobiotica. 2011 Dec;41(12):1063-75.

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