Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000279)
Formula Reactant Apremilast Product Apremilast metabolite M7
Reactant Info Product Info
Metabolic Type Oxidation - N-Deacetylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000277 Apremilast Apremilast metabolite M1/2 Unclear Apremilast [1]
MR000278 Apremilast Apremilast metabolite M17 Oxidation - Hydroxylation Apremilast [1]
MR000280 Apremilast Apremilast metabolite M5 Unclear Apremilast [1]
MR000276 Apremilast O-desmethyl Apremilast Oxidation - O-Demethylation Apremilast [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000267 Apremilast metabolite M7 Apremilast metabolite M11 Oxidation - Hydroxylation Apremilast [1]
MR000268 Apremilast metabolite M7 Apremilast metabolite M4 Oxidation - O-Demethylation Apremilast [1]
References
1 Disposition, metabolism and mass balance of [(14)C]apremilast following oral administration. Xenobiotica. 2011 Dec;41(12):1063-75.

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