Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000277)
Formula Reactant Apremilast Product Apremilast metabolite M1/2
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000278 Apremilast Apremilast metabolite M17 Oxidation - Hydroxylation Apremilast [1]
MR000280 Apremilast Apremilast metabolite M5 Unclear Apremilast [1]
MR000279 Apremilast Apremilast metabolite M7 Oxidation - N-Deacetylation Apremilast [1]
MR000276 Apremilast O-desmethyl Apremilast Oxidation - O-Demethylation Apremilast [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000262 Apremilast metabolite M1/2 Apremilast metabolite M18 Hydrolysis - Hydrolysis Apremilast [1]
MR000261 Apremilast metabolite M1/2 Apremilast metabolite M9 Hydrolysis - Hydrolysis Apremilast [1]
References
1 Disposition, metabolism and mass balance of [(14)C]apremilast following oral administration. Xenobiotica. 2011 Dec;41(12):1063-75.

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