Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000278)
Formula
SVG example
Hydroxylation
Reactant Apremilast Product Apremilast metabolite M17
Reactant Info Product Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000277 Apremilast Apremilast metabolite M1/2 Unclear Apremilast [1]
MR000280 Apremilast Apremilast metabolite M5 Unclear Apremilast [1]
MR000279 Apremilast Apremilast metabolite M7 Oxidation - N-Deacetylation Apremilast [1]
MR000276 Apremilast O-desmethyl Apremilast Oxidation - O-Demethylation Apremilast [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000264 Apremilast metabolite M17 Apremilast metabolite M10 Oxidation - Hydroxylation Apremilast [1]
MR000265 Apremilast metabolite M17 Apremilast metabolite M16 Oxidation - Hydroxylation Apremilast [1]
References
1 Disposition, metabolism and mass balance of [(14)C]apremilast following oral administration. Xenobiotica. 2011 Dec;41(12):1063-75.

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