Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000946)
Formula
SVG example
Reactant Eslicarbazepine acetate Product Eslicarbazepine
Reactant Info Product Info
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001871 Oxcarbazepine Eslicarbazepine Reduction - Reduction Oxcarbazepine [1]
MR000948 Oxcarbazepine Eslicarbazepine Reduction - Reduction Eslicarbazepine acetate [2]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000945 Eslicarbazepine Eslicarbazepine-O-glucuronide metabolite Unclear Eslicarbazepine acetate [3], [4]
MR000944 Eslicarbazepine Oxcarbazepine Oxidation - Oxidation Eslicarbazepine acetate [3], [4]
References
1 The role of carbonyl reducing enzymes in oxcarbazepine in vitro metabolism in man. Chem Biol Interact. 2014 Sep 5;220:241-7.
2 U. S. FDA Label -Eslicarbazepine acetate
3 Pharmacokinetics and drug interactions of eslicarbazepine acetate Epilepsia. 2012 Jun;53(6):935-46. doi: 10.1111/j.1528-1167.2012.03519.x.
4 Key factors in the discovery and development of new antiepileptic drugs Nat Rev Drug Discov. 2010 Jan;9(1):68-82. doi: 10.1038/nrd2997.

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