General Information of This Metabolic Reaction (MR) (ID: MR001169)
Formula
SVG example
Hydroxylation
Reactant Imrecoxib metabolite M4 Product Imrecoxib metabolite M3
Reactant Info Product Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001174 Imrecoxib Imrecoxib metabolite M4 Oxidation - Oxidation Imrecoxib [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001170 Imrecoxib metabolite M4 Imrecoxib metabolite M1 Oxidation - Oxidation Imrecoxib [2]
MR001168 Imrecoxib metabolite M4 Imrecoxib metabolite M2 Oxidation - Oxidation Imrecoxib [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001172 Imrecoxib metabolite M3 Imrecoxib metabolite M7 Conjugation - Glucuronidation Imrecoxib [3]
References
1 Metabolism and excretion of imrecoxib in rat Xenobiotica. 2006 May;36(5):441-55. doi: 10.1080/00498250600595524.
2 Exposures to estradiol, ethinylestradiol and octylphenol affect survival and growth of Rana pipiens and Rana sylvatica tadpoles J Toxicol Environ Health A. 2006 Aug;69(16):1555-69. doi: 10.1080/15287390500470759.
3 Changes in the growth, but not the survival, of American kestrels (Falco sparverius) exposed to environmentally relevant polybrominated diphenyl ethers J Toxicol Environ Health A. 2006 Aug;69(16):1541-54. doi: 10.1080/15287390500468753.

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