Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001345)
Formula Reactant Ketoconazole epoxide intermediate Product Ketoconazole ketone intermediate
Reactant Info Product Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001357 Ketoconazole Ketoconazole epoxide intermediate Unclear Ketoconazole [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001344 Ketoconazole epoxide intermediate Ketoconazole dihydroxyl intermediate Other reaction - Hydration Ketoconazole [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001349 Ketoconazole ketone intermediate Ketoconazole ketone hydroxyl intermediate Other reaction - Hydration Ketoconazole [1]
References
1 Revisiting the metabolism of ketoconazole using accurate mass Drug Metab Lett. 2009 Aug;3(3):191-8. doi: 10.2174/187231209789352085.

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