Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001353)
Formula
SVG example
Deacetylation
Reactant Ketoconazole Product M14 (Ketoconazole)
Reactant Info Product Info
Metabolic Type Oxidation - Deacetylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001357 Ketoconazole Ketoconazole epoxide intermediate Unclear Ketoconazole [1]
MR001352 Ketoconazole M13 (Ketoconazole) Oxidation - N-Oxidation Ketoconazole [1]
MR001354 Ketoconazole M7 (Ketoconazole) Oxidation - Oxidation Ketoconazole [1]
MR001355 Ketoconazole M8 (Ketoconazole) Oxidation - Hydroxylation Ketoconazole [1]
MR001356 Ketoconazole M9 (Ketoconazole) Oxidation - Hydoxylation Ketoconazole [1]
References
1 Revisiting the metabolism of ketoconazole using accurate mass Drug Metab Lett. 2009 Aug;3(3):191-8. doi: 10.2174/187231209789352085.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.