Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001357)
Formula Reactant Ketoconazole Product Ketoconazole epoxide intermediate
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001352 Ketoconazole M13 (Ketoconazole) Oxidation - N-Oxidation Ketoconazole [1]
MR001353 Ketoconazole M14 (Ketoconazole) Oxidation - Deacetylation Ketoconazole [1]
MR001354 Ketoconazole M7 (Ketoconazole) Oxidation - Oxidation Ketoconazole [1]
MR001355 Ketoconazole M8 (Ketoconazole) Oxidation - Hydroxylation Ketoconazole [1]
MR001356 Ketoconazole M9 (Ketoconazole) Oxidation - Hydoxylation Ketoconazole [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001344 Ketoconazole epoxide intermediate Ketoconazole dihydroxyl intermediate Other reaction - Hydration Ketoconazole [1]
MR001345 Ketoconazole epoxide intermediate Ketoconazole ketone intermediate Oxidation - Oxidation Ketoconazole [1]
References
1 Revisiting the metabolism of ketoconazole using accurate mass Drug Metab Lett. 2009 Aug;3(3):191-8. doi: 10.2174/187231209789352085.

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