Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001449)
Formula
	Reactant	Levamlodipine metabolite M9	Product	Levamlodipine metabolite M1
	Reactant	Reactant Info	Product	Product Info

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR001452	Levamlodipine	Levamlodipine metabolite M9	Oxidation - Dehydrogenation	Levamlodipine	[1], [2]

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR001448	Levamlodipine metabolite M9	Levamlodipine metabolite M10	Oxidation - Oxidative Deamination	Levamlodipine	[1], [2]
MR001450	Levamlodipine metabolite M9	Levamlodipine metabolite M4	Oxidation - O-Dealkylation	Levamlodipine	[1], [2]

References
1	Amlodipine metabolism in human liver microsomes and roles of CYP3A4/5 in the dihydropyridine dehydrogenation. Drug Metab Dispos. 2014 Feb;42(2):245-9.
2	Absence of excretion of the active moiety of bisacodyl and sodium picosulfate into human breast milk: an open-label, parallel-group, multiple-dose study in healthy lactating women Drug Metab Pharmacokinet. 2011;26(5):458-64. doi: 10.2133/dmpk.dmpk-11-rg-007.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.