Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002712)
Formula
SVG example
Reactant Eszopiclone Product 2-amino-5-chloropyridine
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002714 Eszopiclone Carbon dioxide Oxidation - Oxidative Decarboxylation Eszopiclone [1]
MR002713 Eszopiclone N-desmethylzopiclone Oxidation - N-Demethylation Eszopiclone [2]
MR002711 Eszopiclone Zopiclone N-oxide Oxidation - N-Oxidation Eszopiclone [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002710 N-desmethylzopiclone 2-amino-5-chloropyridine Unclear Eszopiclone [2]
MR002709 Zopiclone N-oxide 2-amino-5-chloropyridine Unclear Eszopiclone [2]
References
1 IMOVANE (Zopiclone) Product Monograph
2 Development of a novel tandem mass spectrometry method for the quantification of eszopiclone without interference from 2-amino-5-chloropyridine and application in a pharmacokinetic study of rat J Pharm Biomed Anal. 2020 Sep 5;188:113363. doi: 10.1016/j.jpba.2020.113363.

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