Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003519)
Formula Reactant Endoxifen Product 4-endoxifen sulfate
Reactant Info Product Info
Metabolic Enzyme Sulfotransferase 2A1 (SULT2A1) DME Info
Metabolic Type Conjugation - Sulfation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011558 Endoxifen Endoxifen O-Glucuronide Unclear - Unclear Endoxifen [1]
MR011559 Endoxifen Endoxifen Sulfate Unclear - Unclear Endoxifen [1]
MR011557 Endoxifen Norendoxifen Oxidation - Demethylation Endoxifen [1]
MR003518 Endoxifen 4-hydroxytamoxifen sulfate Conjugation - Sulfation Tamoxifen citrate [2]
MR003517 Endoxifen Norendoxifen Oxidation - Demethylation Tamoxifen citrate [2]
MR003520 Endoxifen Tamoxifen glucuronides Conjugation - Glucuronidation Tamoxifen citrate [2]
References
1 Clinical pharmacokinetics and pharmacogenetics of tamoxifen and endoxifen
2 PharmGKB:Tamoxifen citrate

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