Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011557)
Formula Reactant Endoxifen Product Norendoxifen
Reactant Info Product Info
Metabolic Type Oxidation - Demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011558 Endoxifen Endoxifen O-Glucuronide Unclear - Unclear Endoxifen [1]
MR011559 Endoxifen Endoxifen Sulfate Unclear - Unclear Endoxifen [1]
MR003519 Endoxifen 4-endoxifen sulfate Conjugation - Sulfation Tamoxifen citrate [2]
MR003518 Endoxifen 4-hydroxytamoxifen sulfate Conjugation - Sulfation Tamoxifen citrate [2]
MR003520 Endoxifen Tamoxifen glucuronides Conjugation - Glucuronidation Tamoxifen citrate [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013145 (Z)-endoxifen Norendoxifen Oxidation - Demethylation (Z)-endoxifen [1]
References
1 Clinical pharmacokinetics and pharmacogenetics of tamoxifen and endoxifen
2 PharmGKB:Tamoxifen citrate

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