Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003769)
Formula Reactant MK-0859 Metabolite M3 Product MK-0859 Metabolite M12
Reactant Info Product Info
Metabolic Type Oxidation - O-demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003768 MK-0859 Metabolite M1 MK-0859 Metabolite M3 Oxidation - Hydrolyzationn MK-0859 [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003770 MK-0859 Metabolite M3 MK-0859 Metabolite M8 Unclear MK-0859 [2]
References
1 Metabolism and excretion of anacetrapib, a novel inhibitor of the cholesteryl ester transfer protein, in humans. Drug Metab Dispos. 2010 Mar;38(3):474-83.
2 Pharmacokinetics, metabolism, and excretion of anacetrapib, a novel inhibitor of the cholesteryl ester transfer protein, in rats and rhesus monkeys

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