Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003770)
Formula Reactant MK-0859 Metabolite M3 Product MK-0859 Metabolite M8
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003768 MK-0859 Metabolite M1 MK-0859 Metabolite M3 Oxidation - Hydrolyzationn MK-0859 [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003769 MK-0859 Metabolite M3 MK-0859 Metabolite M12 Oxidation - O-demethylation MK-0859 [2]
References
1 Metabolism and excretion of anacetrapib, a novel inhibitor of the cholesteryl ester transfer protein, in humans. Drug Metab Dispos. 2010 Mar;38(3):474-83.
2 Pharmacokinetics, metabolism, and excretion of anacetrapib, a novel inhibitor of the cholesteryl ester transfer protein, in rats and rhesus monkeys

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