Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003809)
Formula Reactant AG-1549 Metabolite C4 Product AG-1549 Metabolite C11
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A1 (Cyp3a1) DME Info
Cytochrome P450 3A2 (Cyp3a2) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003813 AG-1549 Metabolite C12 AG-1549 Metabolite C4 Unclear AG-1549 [1]
MR003808 AG-1549 Metabolite C15 AG-1549 Metabolite C4 Oxidation - Oxidationn AG-1549 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003799 AG-1549 Metabolite C18 AG-1549 Metabolite C11 Oxidation - Oxidationn AG-1549 [1]
MR003801 AG-1549 Metabolite C22 AG-1549 Metabolite C11 Unclear AG-1549 [1]
References
1 Evaluation of capravirine as a CYP3A probe substrate: in vitro and in vivo metabolism of capravirine in rats and dogs

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