Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR003839)
Formula
CYP1A2 ...
SVG example
Hydrolyzationn
Reactant BE-14348A Product Eriodictyol
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1A2 (CYP1A2) DME Info
Cytochrome P450 2C9 (CYP2C9) DME Info
Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 3A5 (CYP3A5) DME Info
Metabolic Type Oxidation - Hydrolyzationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003833 BE-14348A 3-(4-Hydroxyphenyl) propionic acid Unclear BE-14348A [1]
MR003842 BE-14348A 5,7-Dihydroxychromone Unclear BE-14348A [2]
MR003841 BE-14348A Apigenin Oxidation - Dehydrogenation BE-14348A [2]
MR003843 BE-14348A Naringenin-O-glucuronides Conjugation - Glucuronidation BE-14348A [2]
MR003844 BE-14348A Phloroglucinol Unclear BE-14348A [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007030 Hesperetin Eriodictyol Oxidation - 4'-demethylation Hesperetin [3]
MR004320 Naringenin Eriodictyol Oxidation - Hydrolyzationn Naringin [4]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003840 Eriodictyol Hesperetin Conjugation - Methylationn BE-14348A [2]
MR004321 Eriodictyol Hesperetin Conjugation - Methylationn Naringin [4]
References
1 High gastrointestinal permeability and local metabolism of naringenin: influence of antibiotic treatment on absorption and metabolism
2 Pharmacokinetics and Metabolism of Naringin and Active Metabolite Naringenin in Rats, Dogs, Humans, and the Differences Between Species
3 DrugBank(Pharmacology-Metabolism):Hesperetin
4 Microbial Metabolism of Naringin and the Impact on Antioxidant Capacity

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